Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26746718 | 0.84 | ALDH1A1 (0.41) | ALDH1A1PKMHPGDKDM4EMAPT | |
| SCHEMBL24796164 | 0.84 | ALDH1A1 (0.41) | ALDH1A1PKMHPGDKDM4EMAPT | |
| SCHEMBL21384318 | 0.84 | ALDH1A1 (0.49) | ALDH1A1PKMHPGDKDM4EMAPT | |
| SCHEMBL21389206 | 0.83 | ALDH1A1 (0.46) | ALDH1A1PKMHPGDKDM4EMAPT | |
| SCHEMBL21389534 | 0.82 | HDAC3 (0.41) | ALDH1A1HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL21389407 | 0.82 | KMT2A (0.42) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL21389320 | 0.77 | CA9 (0.41) | ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL24796162 | 0.76 | CYP1A2 (0.42) | ALDH1A1PKMKDM4EPOLBKMT2A | |
| SCHEMBL21389424 | 0.73 | KMT2A (0.31) | KMT2A | |
| SCHEMBL21389426 | 0.72 | KMT2A (0.52) | KDM4EPOLBKMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |