SCHEMBL21389500

SCHEMBL21389500

C[C@H]1CC(=O)N(CCNC(=O)CSCC(=O)NC2CCCC2)C1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.43
▸ HPGD P15428 6/20 0.42
▸ KMT2A Q03164 3/20 0.42
▸ SMN1; SMN2 Q16637 3/20 0.42
▸ LMNA P02545 1/20 0.42
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ GAA P10253 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ POLB P06746 3/20 0.38
▸ RXFP1 Q9HBX9 1/20 0.38
▸ ALDH1A1 P00352 2/20 0.37
▸ NPC1 O15118 1/20 0.37
▸ RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796314 1.00 L3MBTL1 (0.43) L3MBTL1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL24796315 0.87 HPGD (0.43) L3MBTL1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL24796415 0.87 HPGD (0.43) L3MBTL1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL21389191 0.86 HPGD (0.44) L3MBTL1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL24796322 0.86 L3MBTL1 (0.41) L3MBTL1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL24796024 0.86 L3MBTL1 (0.41) L3MBTL1HPGDKMT2ASMN1; SMN2LMNA
SCHEMBL21383860 0.84 USP2 (0.37) L3MBTL1KMT2ALMNACYP2C19GAA
SCHEMBL21389303 0.84 USP2 (0.37) L3MBTL1KMT2ALMNACYP2C19GAA
SCHEMBL26746513 0.84 KMT2A (0.37) KMT2ACYP3A4CYP2C19MEN1POLB
SCHEMBL26634661 0.84 USP2 (0.37) L3MBTL1KMT2ALMNACYP2C19GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR L3MBTL1 2161/4885HPGD 2144/4885KMT2A 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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