Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22617106 | 0.86 | ATF4 (0.71) | ATF4 | |
| SCHEMBL30024698 | 0.84 | ATF4 (0.79) | ATF4 | |
| SCHEMBL19569507 | 0.84 | ATF4 (0.79) | ATF4 | |
| SCHEMBL25834026 | 0.83 | ATF4 (0.65) | ATF4 | |
| SCHEMBL20974057 | 0.82 | ATF4 (0.72) | ATF4 | |
| SCHEMBL19569259 | 0.82 | ATF4 (0.72) | ATF4 | |
| SCHEMBL19569443 | 0.82 | ATF4 (0.60) | ATF4 | |
| SCHEMBL32682101 | 0.82 | ATF4 (0.72) | ATF4 | |
| SCHEMBL19569580 | 0.81 | ATF4 (0.72) | ATF4 | |
| SCHEMBL19569488 | 0.81 | ATF4 (0.72) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183589-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. (US) | 2019-09-26 | — | — | WO | disclosed |