Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 16/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390160 | 1.00 | ATF4 (0.65) | ATF4KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL23294602 | 1.00 | ATF4 (0.65) | ATF4KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL21389950 | 0.88 | ATF4 (0.48) | ATF4ALDH1A1 | |
| SCHEMBL25962112 | 0.86 | ATF4 (0.69) | ATF4KCNH2MEN1KMT2A | |
| SCHEMBL20610375 | 0.84 | ATF4 (0.78) | ATF4KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL20610419 | 0.82 | ATF4 (0.74) | ATF4KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL20610407 | 0.81 | ATF4 (0.72) | ATF4KCNH2MEN1ALDH1A1KMT2A | |
| SCHEMBL21390089 | 0.81 | ATF4 (0.75) | ATF4KCNH2 | |
| SCHEMBL21390085 | 0.81 | ATF4 (0.75) | ATF4KCNH2 | |
| SCHEMBL21390135 | 0.81 | ATF4 (0.75) | ATF4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183589-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. (US) | 2019-09-26 | — | — | WO | disclosed |