Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390095 | 0.91 | ATF4 (0.59) | ATF4 | |
| SCHEMBL21390197 | 0.88 | ATF4 (0.76) | ATF4 | |
| SCHEMBL23294612 | 0.88 | ATF4 (0.76) | ATF4 | |
| SCHEMBL21390104 | 0.88 | ATF4 (0.76) | ATF4 | |
| SCHEMBL21389964 | 0.87 | ATF4 (0.77) | ATF4 | |
| SCHEMBL19569490 | 0.85 | ATF4 (0.57) | ATF4 | |
| SCHEMBL19569260 | 0.84 | ATF4 (0.56) | ATF4 | |
| SCHEMBL19569769 | 0.84 | ATF4 (0.56) | ATF4 | |
| SCHEMBL19569020 | 0.83 | ATF4 (0.46) | ATF4 | |
| SCHEMBL19569759 | 0.82 | ATF4 (0.56) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183589-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. (US) | 2019-09-26 | — | — | WO | disclosed |