Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770430 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL14789140 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL26460947 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL14037653 | 0.97 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL20284982 | 0.97 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL20333040 | 0.94 | ALDH1A1 (0.47) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL7745275 | 0.92 | ALDH1A1 (0.47) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL18898243 | 0.91 | CXCR4 (0.41) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL19889810 | 0.89 | ALDH1A1 (0.42) | ALDH1A1CXCR4SMN1; SMN2 | |
| SCHEMBL19840407 | 0.88 | CXCR4 (0.47) | ALDH1A1CXCR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183589-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. (US) | 2019-09-26 | — | — | WO | disclosed |