Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23234238 | 1.00 | MGLL (0.83) | MGLL | |
| SCHEMBL23211694 | 1.00 | MGLL (0.83) | MGLL | |
| SCHEMBL30149616 | 1.00 | MGLL (0.83) | MGLL | |
| SCHEMBL23211695 | 1.00 | MGLL (0.83) | MGLL | |
| SCHEMBL21390475 | 0.96 | MGLL (0.76) | MGLL | |
| SCHEMBL21390332 | 0.96 | MGLL (0.76) | MGLL | |
| SCHEMBL23176599 | 0.96 | MGLL (0.76) | MGLL | |
| SCHEMBL23150515 | 0.96 | MGLL (0.76) | MGLL | |
| SCHEMBL23150516 | 0.96 | MGLL (0.76) | MGLL | |
| SCHEMBL23211786 | 0.94 | MGLL (0.89) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768684-B1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | HOFFMANN LA ROCHE (CH) | 2023-02-22 | — | — | EP | disclosed |
| WO-2019180185-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-09-26 | — | — | WO | disclosed |