Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148887 | 1.00 | MGLL (0.71) | MGLL | |
| SCHEMBL29849894 | 1.00 | MGLL (0.71) | MGLL | |
| SCHEMBL25785716 | 0.95 | MGLL (0.70) | MGLL | |
| SCHEMBL24095543 | 0.95 | MGLL (0.70) | MGLL | |
| SCHEMBL23853793 | 0.90 | MGLL (0.63) | MGLL | |
| SCHEMBL32685333 | 0.90 | MGLL (0.63) | MGLL | |
| SCHEMBL21390254 | 0.86 | MGLL (0.62) | MGLL | |
| SCHEMBL23149104 | 0.86 | MGLL (0.73) | MGLL | |
| SCHEMBL21390125 | 0.86 | MGLL (0.73) | MGLL | |
| SCHEMBL23150511 | 0.83 | MGLL (1.00) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768684-B1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | HOFFMANN LA ROCHE (CH) | 2023-02-22 | — | — | EP | disclosed |
| WO-2019180185-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-09-26 | — | — | WO | disclosed |