⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25469271 | 0.86 | — | — | |
| SCHEMBL22025268 | 0.80 | PAOX (0.41) | — | |
| SCHEMBL24383376 | 0.80 | PAOX (0.41) | — | |
| SCHEMBL10939348 | 0.79 | GPR84 (0.32) | — | |
| SCHEMBL22025175 | 0.78 | — | — | |
| SCHEMBL15183700 | 0.76 | CAMK2A (0.31) | — | |
| SCHEMBL23197900 | 0.76 | — | — | |
| SCHEMBL20158894 | 0.74 | SPHK2 (0.30) | — | |
| SCHEMBL20833084 | 0.73 | — | — | |
| SCHEMBL19861254 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |