Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390843 | 0.84 | CYP19A1 (0.33) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21390946 | 0.84 | CYP19A1 (0.35) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21390897 | 0.84 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21391110 | 0.84 | CYP19A1 (0.33) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21391163 | 0.84 | CYP19A1 (0.32) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21390771 | 0.84 | CYP19A1 (0.32) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21391103 | 0.83 | HDAC1 (0.33) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21390898 | 0.83 | HDAC1 (0.32) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21390945 | 0.82 | CYP19A1 (0.33) | CYP19A1CYP11B1CYP11B2CDK4CCND1 | |
| SCHEMBL21390923 | 0.81 | CYP19A1 (0.34) | CYP19A1CYP11B1CYP11B2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |