Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391103 | 0.89 | HDAC1 (0.33) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390826 | 0.84 | CACNA1H (0.35) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390822 | 0.83 | CYP19A1 (0.33) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL23132029 | 0.83 | HDAC1 (0.33) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390672 | 0.81 | BRD4 (0.34) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390933 | 0.81 | CDK4 (0.32) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21391163 | 0.81 | CYP19A1 (0.32) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390935 | 0.80 | HDAC1 (0.33) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390843 | 0.80 | CYP19A1 (0.33) | HDAC1CDK4CCND1CCND3CDK6 | |
| SCHEMBL21354613 | 0.80 | EGFR (0.36) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |