Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390853 | 0.97 | RORC (0.32) | RORCCYP11B1CYP11B2PDE4BPDE4D | |
| SCHEMBL21390848 | 0.91 | RORC (0.33) | RORCCYP11B1CYP11B2PDE4BPDE4D | |
| SCHEMBL21391139 | 0.88 | NPC1 (0.35) | RORCPDE4BPDE4D | |
| SCHEMBL21391135 | 0.88 | NPC1 (0.35) | RORCPDE4BPDE4D | |
| SCHEMBL21390851 | 0.84 | RORC (0.31) | RORC | |
| SCHEMBL21390990 | 0.84 | RORC (0.32) | RORCCYP11B1CYP11B2 | |
| SCHEMBL21390954 | 0.83 | RORC (0.32) | RORCCYP11B1CYP11B2 | |
| SCHEMBL21391012 | 0.83 | CYP11B1 (0.32) | RORCCYP11B1CYP11B2 | |
| SCHEMBL21390916 | 0.83 | RORC (0.32) | RORC | |
| SCHEMBL21390855 | 0.81 | RORC (0.33) | RORCCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |