Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390907 | 1.00 | RORC (0.32) | RORCMGLLPDE2A | |
| SCHEMBL21390954 | 0.91 | RORC (0.32) | RORCMGLL | |
| SCHEMBL21390916 | 0.89 | RORC (0.32) | RORC | |
| SCHEMBL21390990 | 0.88 | RORC (0.32) | RORC | |
| SCHEMBL21390918 | 0.88 | RORC (0.34) | RORC | |
| SCHEMBL21391012 | 0.87 | CYP11B1 (0.32) | RORC | |
| SCHEMBL21391134 | 0.87 | RORC (0.33) | RORC | |
| SCHEMBL21390906 | 0.86 | PDE2A (0.31) | PDE2A | |
| SCHEMBL21390848 | 0.85 | RORC (0.33) | RORCMGLL | |
| SCHEMBL21390904 | 0.85 | PDE2A (0.32) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |