Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391081 | 0.81 | PDE2A (0.41) | CDK4CDK2CDK6CDK1CDK7 | |
| SCHEMBL21390939 | 0.78 | PDE2A (0.41) | CDK4CDK2CDK6CDK1CDK7 | |
| SCHEMBL10002805 | 0.74 | EGFR (0.35) | PRPS1ACACB | |
| SCHEMBL30038519 | 0.73 | CDK6 (0.43) | CDK4CDK2CDK6CDK1CDK5 | |
| SCHEMBL18191711 | 0.73 | CDK6 (0.43) | CDK4CDK2CDK6CDK1CDK5 | |
| SCHEMBL18791651 | 0.73 | ACACB (0.35) | ACACB | |
| SCHEMBL18779250 | 0.73 | KCNQ2 (0.35) | ACACB | |
| SCHEMBL21539307 | 0.72 | ACACB (0.39) | CDK4CDK2CDK6CCND3PRPS1 | |
| SCHEMBL31257710 | 0.72 | CCNE1 (0.35) | CDK4CDK2CDK6CDK9CCND3 | |
| SCHEMBL18202603 | 0.71 | CDK4 (0.37) | CDK4CDK2CDK6CDK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |