Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21272609 | 0.81 | HMGCR (0.64) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL7041938 | 0.79 | HMGCR (0.58) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL123396 | 0.73 | — | — | |
| SCHEMBL21272706 | 0.73 | GAA (0.41) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL29229017 | 0.72 | — | — | |
| SCHEMBL3903716 | 0.72 | — | — | |
| SCHEMBL14644733 | 0.72 | — | — | |
| SCHEMBL15113111 | 0.71 | — | — | |
| SCHEMBL11289793 | 0.71 | — | — | |
| SCHEMBL22438757 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |