Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPEPPS | P55786 | 13/20 | 0.82 |
| ▸ | ANPEP | P15144 | 9/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.82 |
| ▸ | TP53 | P04637 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.82 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | NPC1 | O15118 | 1/20 | 0.81 |
| ▸ | RAB9A | P51151 | 1/20 | 0.81 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23056386 | 1.00 | NPEPPS (0.82) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL21418055 | 0.94 | NPEPPS (0.83) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL23056423 | 0.94 | NPEPPS (0.83) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL23056387 | 0.94 | NPEPPS (0.83) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL18300018 | 0.92 | NPEPPS (0.81) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL29703340 | 0.92 | NPEPPS (0.83) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL20304578 | 0.92 | NPEPPS (0.83) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL23056399 | 0.92 | NPEPPS (0.69) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| SCHEMBL20393654 | 0.91 | NPEPPS (0.76) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 | |
| Puromycin SCHEMBL22348910 | 0.90 | NPEPPS (1.00) | NPEPPSANPEPSMN1; SMN2TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183270-A1 | PUROMYCIN-BASED PROBES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |