Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 3/20 | 0.57 |
| ▸ | CSF1R | P07333 | 1/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.57 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20707292 | 0.88 | KIT (0.75) | KITCSF1RPDGFRBDDR1KMT2A | |
| SCHEMBL28320364 | 0.85 | KIT (0.54) | KITCSF1RPDGFRBDDR1KDM4E | |
| SCHEMBL21391331 | 0.82 | KIT (0.77) | KITCSF1RPDGFRBDDR1KMT2A | |
| SCHEMBL21391333 | 0.81 | KIT (0.58) | KITCSF1RPDGFRBDDR1KMT2A | |
| SCHEMBL21385153 | 0.80 | KIT (0.66) | KITCSF1RPDGFRBDDR1KMT2A | |
| SCHEMBL29634986 | 0.80 | KIT (0.66) | KITCSF1RPDGFRBDDR1KMT2A | |
| SCHEMBL21391340 | 0.80 | KIT (0.59) | KITCSF1RPDGFRBDDR1KMT2A | |
| SCHEMBL21391338 | 0.80 | KIT (0.66) | KITCSF1RPDGFRBDDR1KDM4E | |
| SCHEMBL21765007 | 0.80 | KDM1A (0.57) | KDM4EPKMKMT2AGPR119PDE4A | |
| SCHEMBL21391327 | 0.79 | KMT2A (0.59) | KITCSF1RPDGFRBDDR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283160-B | PDGFR kinase inhibitor | 中国科学院合肥物质科学研究院 | 2022-04-29 | — | — | CN | disclosed |
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |