Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 3/20 | 0.48 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695968 | 0.89 | PDGFRB (0.59) | PRKAA2CSF1RPDGFRBKITDDR1 | |
| SCHEMBL21391336 | 0.85 | CSF1R (0.57) | PRKAA2CSF1RPDGFRBKITDDR1 | |
| SCHEMBL21391334 | 0.84 | KIT (0.62) | CSF1RPDGFRBKITDDR1NPC1 | |
| SCHEMBL20707305 | 0.83 | CSF1R (0.51) | CSF1RPDGFRBKITDDR1MAPT | |
| SCHEMBL3289150 | 0.81 | SMO (0.44) | PRKAA2SCD5NPC1RAB9AGAA | |
| SCHEMBL5152018 | 0.80 | PRKAA2 (0.44) | PRKAA2SCD5CSF1RPDGFRBKIT | |
| SCHEMBL21391337 | 0.79 | KCNK3 (0.56) | NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL10262389 | 0.78 | RAB9A (0.59) | NPC1RAB9ANLRP3OPRK1F2 | |
| SCHEMBL3288508 | 0.78 | PRKAA2 (0.44) | PRKAA2CSF1RPDGFRBKITDDR1 | |
| Hydrochloric Acid SCHEMBL4508721 | 0.78 | NPC1 (0.57) | NPC1RAB9ANLRP3OPRK1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |