Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.66 |
| ▸ | CSF1R | P07333 | 1/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.66 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.66 |
| ▸ | BRAF | P15056 | 16/20 | 0.49 |
| ▸ | RAF1 | P04049 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391318 | 0.92 | CSF1R (0.55) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL20695966 | 0.91 | KIT (0.79) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391334 | 0.86 | KIT (0.62) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391406 | 0.86 | KIT (0.57) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391412 | 0.84 | CSF1R (0.62) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391416 | 0.84 | CSF1R (0.61) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391376 | 0.83 | KIT (0.63) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391381 | 0.83 | KIT (0.61) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391415 | 0.83 | CSF1R (0.60) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL20695975 | 0.81 | KIT (0.60) | KITCSF1RPDGFRBDDR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |