Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.61 |
| ▸ | CSF1R | P07333 | 2/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.61 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.61 |
| ▸ | ABL1 | P00519 | 3/20 | 0.49 |
| ▸ | BRAF | P15056 | 16/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.49 |
| ▸ | RAF1 | P04049 | 4/20 | 0.48 |
| ▸ | YES1 | P07947 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | BLK | P51451 | 1/20 | 0.46 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695973 | 0.90 | KIT (0.75) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391328 | 0.87 | KIT (0.57) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391412 | 0.84 | CSF1R (0.62) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391416 | 0.83 | CSF1R (0.61) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL21391377 | 0.83 | KIT (0.66) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391376 | 0.83 | KIT (0.63) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391415 | 0.82 | CSF1R (0.60) | KITCSF1RPDGFRBDDR1BRAF | |
| SCHEMBL20707331 | 0.78 | KIT (0.79) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391401 | 0.77 | KIT (0.46) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20707298 | 0.76 | KIT (0.89) | KITCSF1RPDGFRBDDR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |