Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 5/20 | 0.56 |
| ▸ | CSF1R | P07333 | 2/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.56 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | BLK | P51451 | 1/20 | 0.48 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391366 | 0.91 | KIT (0.57) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391420 | 0.91 | KIT (0.57) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391361 | 0.90 | KIT (0.57) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391395 | 0.89 | KIT (0.56) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391405 | 0.88 | KIT (0.59) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391367 | 0.87 | KIT (0.68) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21385153 | 0.85 | KIT (0.66) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL29634986 | 0.85 | KIT (0.66) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391365 | 0.85 | KIT (0.54) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391402 | 0.83 | KIT (0.55) | KITCSF1RPDGFRBDDR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |