Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 11/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811268 | 1.00 | CYP2C19 (0.60) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL934056 | 0.78 | CYP2C19 (0.70) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL11161107 | 0.76 | CYP2C19 (0.47) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL1766985 | 0.76 | CYP2C19 (1.00) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL2400082 | 0.76 | CYP2C19 (0.66) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL17762784 | 0.76 | CYP2C19 (0.66) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL20543720 | 0.75 | CTSC (0.55) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL1670312 | 0.75 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL288244 | 0.75 | CYP2C19 (0.70) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL16683907 | 0.75 | CYP2C19 (0.70) | CYP2C19SLC1A3SLC1A2SLC1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906669-B2 | Metallocene-based phosphorus chiral phosphines | SOLVIAS AG (CH) | 2011-03-15 | — | — | US | disclosed |
| EP-1844061-B1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | SOLVIAS AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| US-20090137824-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | PHOENIX CHEMICALS LTD (GB) | 2009-05-28 | — | — | US | disclosed |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| EP-1844061-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | Phoenix Chemicals Limited (GB) | 2007-10-17 | — | — | EP | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075166-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137824-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | POLL, ZNF207, ZC3HAV1L | CYP2C19 1029/4885SLC1A3 2731/4885SLC1A2 2272/4885 |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | AS3MT, PPA1, AGPS | CYP2C19 733/4885SLC1A3 278/4885SLC1A2 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.