Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.69 |
| ▸ | PPARG | P37231 | 13/20 | 0.69 |
| ▸ | PPARD | Q03181 | 6/20 | 0.69 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993002 | 1.00 | PPARA (0.69) | PPARAPPARGPPARDSRR | |
| SCHEMBL15246753 | 0.87 | PPARA (0.56) | PPARAPPARGPPARDSRR | |
| Ethylene SCHEMBL5331457 | 0.87 | PPARA (0.65) | PPARAPPARGPPARDSRR | |
| SCHEMBL16415813 | 0.87 | PPARA (0.92) | PPARAPPARGPPARD | |
| SCHEMBL5993963 | 0.87 | PPARA (0.92) | PPARAPPARGPPARD | |
| SCHEMBL5608022 | 0.87 | PPARA (0.92) | PPARAPPARGPPARD | |
| SCHEMBL543815 | 0.86 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL17680422 | 0.86 | PPARA (0.68) | PPARAPPARGPPARD | |
| SCHEMBL3541115 | 0.86 | MMP8 (0.56) | PPARAPPARGPPARDSRR | |
| SCHEMBL5543269 | 0.86 | PPARA (0.72) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101133040-A | Novel heterocyclic oxime derivatives, method for preparing same and use thereof as hypoglycaemic or hypolipidemic agents | SERVIER LAB (FR) | 2008-02-27 | — | — | CN | claimed |
| CN-101133028-A | Novel heterocyclic oxime derivatives, method for preparing same and pharmaceutical compositions containing same | SERVIER LAB (FR) | 2008-02-27 | — | — | CN | claimed |
| CN-1558758-A | Novel pyrrole compound with blood fat and cholesterol reducing activity, preparation method thereof, pharmaceutical composition containing same and medical application thereof | — | 2004-12-29 | — | — | CN | claimed |
| CN-110099898-A | compound and use thereof | 优曼尼蒂治疗公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-106068256-A | Benzodiazepine derivatives, compositions and methods for treating cognitive impairment | 艾吉恩生物股份有限公司 | 2016-11-02 | — | — | CN | disclosed |
| US-20160296592-A1 | Methods and Compositions for the Treatment of Proteinuric Diseases | THE GENERAL HOSPITAL CORPORATION | 2016-10-13 | — | — | US | disclosed |
| CN-102123763-B | Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use thereof | XENOPORT, INC. (US) | 2014-10-08 | — | — | CN | disclosed |
| CN-102448933-B | Indole Derivatives as PBR Ligands | GE HEALTHCARE LTD | 2014-07-02 | — | — | CN | disclosed |
| CN-103517897-A | Synthesis of cyclopentaquinazolines | ONYX PHARMA INC | 2014-01-15 | — | — | CN | disclosed |
| EP-2488500-A1 | SPIROPIPERIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF FOR TREATING DIABETES | Eli Lilly and Company (US) | 2012-08-22 | — | — | EP | disclosed |
| CN-102448933-A | Indole Derivatives as PBR Ligands | GE HEALTHCARE LTD | 2012-05-09 | — | — | CN | disclosed |
| EP-1237854-A1 | COMMINUTED FORM OF (S)-2-ETHOXY -3- 4-(2- 4-METHANESULFONYLOXYPHENYL ETHOXY) PHENYL] PROPANOIC ACID | AstraZeneca AB (SE) | 2002-09-11 | — | — | EP | disclosed |
| CN-1352639-A | Novel tricyclic compounds and their use in medicine, process for their production and pharmaceutical composition containing them | REDDY RESEARCH FOUNDATION (IN) | 2002-06-05 | — | — | CN | disclosed |
| WO-2001040169-A1 | COMMINUTED FORM OF (S)-2-ETHOXY -3-[4-(2- {4-METHANESULFONYLOXYPHENYL} ETHOXY) PHENYL] PROPANOIC ACID | ASTRAZENECA AB (SE) | 2001-06-07 | — | — | WO | disclosed |
| EP-1084102-A1 | NEW 3-ARYL PROPIONIC ACID DERIVATIVES AND ANALOGS | AstraZeneca AB (SE) | 2001-03-21 | — | — | EP | disclosed |
| CN-1280575-A | Novel tricyclic compounds and their use as medicaments, process for their preparation and pharmaceutical compositions containing them | REDDY CHEMINOR INC (IN) | 2001-01-17 | — | — | CN | disclosed |
| EP-0758013-B1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL CO LTD (JP) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999062871-A1 | NEW 3-ARYL PROPIONIC ACID DERIVATIVES AND ANALOGS | ASTRAZENECA AB (SE) | 1999-12-09 | — | — | WO | disclosed |
| US-5855971-A | Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film | NIPPON OIL COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0758013-A1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160296592-A1 | Methods and Compositions for the Treatment of Proteinuric Diseases | ITGB3, PLAUR, PROC | PPARA 3054/4885PPARG 2468/4885PPARD 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.