Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.54 |
| ▸ | ATP4A | P20648 | 2/20 | 0.36 |
| ▸ | ATP4B | P51164 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391529 | 0.84 | DHODH (0.56) | DHODHATP4AATP4B | |
| SCHEMBL24141937 | 0.77 | DHODH (0.67) | DHODH | |
| SCHEMBL21391587 | 0.77 | DHODH (0.50) | DHODHATP4AATP4BSIRT5 | |
| SCHEMBL21391594 | 0.77 | DHODH (0.48) | DHODHATP4AATP4B | |
| SCHEMBL21391527 | 0.75 | DHODH (0.64) | DHODH | |
| SCHEMBL21391596 | 0.74 | DHODH (0.48) | DHODHATP4AATP4B | |
| SCHEMBL24142079 | 0.74 | DHODH (0.70) | DHODH | |
| SCHEMBL21391550 | 0.72 | DHODH (0.51) | DHODH | |
| SCHEMBL24141938 | 0.71 | DHODH (0.53) | DHODHATP4AATP4BSIRT5 | |
| SCHEMBL20836148 | 0.70 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | FABP2, SLC10A2, ALPI | DHODH 803/4885ATP4A 1371/4885ATP4B 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.