SCHEMBL21391492

SCHEMBL21391492

Cc1ccc(Oc2ccc(N(CCN(c3ccccc3)c3ccc(Oc4ccc(C)cc4)cc3)c3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
HTT P42858 1/20 0.47
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
TEAD4 Q15561 1/20 0.44
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
LTA4H P09960 3/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PTGES O14684 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPK14 Q16539 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
FFAR1 O14842 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14732511 0.82 HTT (0.52) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL15729985 0.82 HTT (0.52) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL14732541 0.82 HTT (0.52) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL172867 0.82 HTT (0.52) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL8944029 0.82 HTT (0.52) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL23254850 0.82 HTT (0.52) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL257146 0.81 MAOA (0.61) NR3C1SMN1; SMN2MTNR1AMTNR1BTEAD4
SCHEMBL20059338 0.81 HTT (0.55) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL12900151 0.81 HTT (0.50) NR3C1SMN1; SMN2HTTTEAD4HTR2A
SCHEMBL12900155 0.81 HTT (0.50) NR3C1SMN1; SMN2HTTTEAD4HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-20240019738-A1 DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF JAPAN DISPLAY INC. (JP) 2024-01-18 US disclosed
US-10761375-B2 Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-09-01 US disclosed
WO-2019182071-A1 LIQUID CRYSTAL ALIGNMENT AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed
WO-2019182072-A1 POLYUREA COPOLYMER, LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed