Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625450 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL18309264 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL27689071 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL24257396 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL17547709 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL24641098 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL3754131 | 1.00 | GBA1 (0.49) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL18051737 | 0.98 | GBA1 (0.46) | GBA1GAASPHK2SPHK1 | |
| SCHEMBL8347365 | 0.92 | GBA1 (0.46) | GBA1GAA | |
| SCHEMBL23848882 | 0.92 | GBA1 (0.46) | GBA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11179482-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2021-11-23 | — | — | US | disclosed |
| US-20200237932-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2020-07-30 | — | — | US | disclosed |
| US-10660974-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2020-05-26 | — | — | US | disclosed |
| US-20190290787-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10660974-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | DAXX, DCAF15, DCAF1 | GBA1 2151/4885GAA 2770/4885SPHK2 4202/4885 |
| US-20200237932-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | DAXX, DCAF15, CDY1; CDY1B | GBA1 1657/4885GAA 2453/4885SPHK2 3544/4885 |
| US-11179482-B2 | Chemiluminescent probes for diagnostics and in vivo imaging | DAXX, DCAF15, CDY1; CDY1B | GBA1 1657/4885GAA 2453/4885SPHK2 3544/4885 |
| US-20190290787-A1 | CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING | DAXX, DCAF15, DCAF1 | GBA1 2151/4885GAA 2770/4885SPHK2 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.