SCHEMBL17547709

SCHEMBL17547709

CCCCCCC[C@@H]1OC(CO)[C@H](O)[C@H](O)C1O

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 5/20 0.49
GAA P10253 1/20 0.49
SPHK2 Q9NRA0 3/20 0.46
SPHK1 Q9NYA1 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25625450 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL18309264 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL21391555 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL27689071 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL24257396 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL24641098 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL3754131 1.00 GBA1 (0.49) GBA1GAASPHK2SPHK1
SCHEMBL18051737 0.98 GBA1 (0.46) GBA1GAASPHK2SPHK1
SCHEMBL8347365 0.92 GBA1 (0.46) GBA1GAA
SCHEMBL23848882 0.92 GBA1 (0.46) GBA1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230181607-A1 THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION The University of the Regents of California (US) 2023-06-15 US disclosed
US-20180111955-A1 THIOSACCHARIDE MUCOLYTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-26 US disclosed
US-9856283-B2 Thiosaccharide mucolytic agents THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-01-02 US disclosed
US-20160060284-A1 THIOSACCHARIDE MUCOLYTIC AGENTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180111955-A1 THIOSACCHARIDE MUCOLYTIC AGENTS MUC1, TREH, FUT6 GBA1 161/4885GAA 86/4885SPHK2 801/4885
US-20160060284-A1 THIOSACCHARIDE MUCOLYTIC AGENTS MUC1, TREH, FUT6 GBA1 161/4885GAA 86/4885SPHK2 801/4885
US-20230181607-A1 THIOSACCHARIDES FOR USE IN TREATING CORONAVIRUS INFECTION TMPRSS4, ACE, ACE2 GBA1 361/4885GAA 672/4885SPHK2 1233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.