Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 7/20 | 0.47 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | MRE11 | P49959 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391587 | 0.85 | DHODH (0.50) | DHODHATP4AATP4BMAPTMEN1 | |
| SCHEMBL21391596 | 0.83 | DHODH (0.48) | DHODHATP4AATP4BMAPTMEN1 | |
| SCHEMBL19631419 | 0.74 | DHODH (0.80) | DHODHATP4AATP4BMAPTALDH1A1 | |
| SCHEMBL21391550 | 0.71 | DHODH (0.51) | DHODHALDH1A1LMNA | |
| SCHEMBL25613755 | 0.69 | DHODH (0.56) | DHODHMAPTMEN1KMT2ALMNA | |
| SCHEMBL25614262 | 0.68 | DHODH (0.53) | DHODHATP4AATP4BMAPTMEN1 | |
| SCHEMBL25614522 | 0.68 | DHODH (0.58) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL25614252 | 0.67 | DHODH (0.65) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21391594 | 0.66 | DHODH (0.48) | DHODHATP4AATP4B | |
| SCHEMBL21391529 | 0.65 | DHODH (0.56) | DHODHATP4AATP4BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2022-12-27 | — | — | US | disclosed |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11534427-B2 | Applications of novel thiazole derivative in treating inflammatory bowel diseases | FABP2, SLC10A2, ALPI | DHODH 803/4885ATP4A 1371/4885ATP4B 1783/4885 |
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | FABP2, SLC10A2, ALPI | DHODH 803/4885ATP4A 1371/4885ATP4B 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.