Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806813 | 0.90 | PLA2G2A (0.63) | PLA2G2ARARBMAPK1NR1H4GRIN2D | |
| SCHEMBL21391915 | 0.84 | PLA2G2A (0.69) | PLA2G2ARARBMAPK1KMT2ATP53 | |
| SCHEMBL19806815 | 0.83 | PLA2G2A (0.77) | PLA2G2ARARBMAPK1KMT2ATP53 | |
| SCHEMBL1107679 | 0.75 | GCK (0.50) | PLA2G2ARARB | |
| SCHEMBL23516920 | 0.74 | PLA2G2A (0.59) | PLA2G2ARARBMAPK1NR1H4GRIN2D | |
| SCHEMBL6539739 | 0.74 | MAPK1 (0.84) | RARBMAPK1TP53TSHR | |
| SCHEMBL10169578 | 0.74 | MAPK1 (0.62) | PLA2G2ARARBMAPK1NR1H4KMT2A | |
| SCHEMBL10137630 | 0.72 | MAPK1 (0.60) | PLA2G2ARARBMAPK1NR1H4KMT2A | |
| SCHEMBL418506 | 0.72 | MAPK1 (0.60) | PLA2G2ARARBMAPK1NR1H4KMT2A | |
| SCHEMBL4276418 | 0.72 | PLA2G2A (0.54) | PLA2G2ARARBMAPK1NR1H4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034720-B2 | Thiol-yne based peptide stapling and uses thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-06-15 | — | — | US | disclosed |
| US-20190292218-A1 | THIOL-YNE BASED PEPTIDE STAPLING AND USES THEREOF | UNIVERSITY OF UTAH | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292218-A1 | THIOL-YNE BASED PEPTIDE STAPLING AND USES THEREOF | IAPP, TP53, GLP1R | PLA2G2A 4711/4885RARB 4776/4885MAPK1 4332/4885 |
| US-11034720-B2 | Thiol-yne based peptide stapling and uses thereof | IAPP, TP53, GLP1R | PLA2G2A 4711/4885RARB 4776/4885MAPK1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.