Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | ICMT | O60725 | 4/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | CDK4 | P11802 | 2/20 | 0.52 |
| ▸ | CCND1 | P24385 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120174 | 0.89 | GPR17 (0.56) | HPGDCYP2C19CDK4CCND1PTGER1 | |
| SCHEMBL23226253 | 0.88 | HPGD (0.61) | HPGDCYP2C19ICMTCDK4CCND1 | |
| SCHEMBL14605596 | 0.86 | NR4A2 (0.57) | HPGDCYP2C19ICMTNR4A2CDK4 | |
| SCHEMBL4605998 | 0.85 | NR4A2 (0.60) | HPGDCYP2C19ICMTNR4A2CDK4 | |
| SCHEMBL30261856 | 0.85 | TSHR (0.66) | HPGDICMTNR4A2CNR2TRPV1 | |
| SCHEMBL23701757 | 0.85 | TSHR (0.66) | HPGDICMTNR4A2CNR2TRPV1 | |
| SCHEMBL24453252 | 0.84 | HTR2C (0.62) | ICMTNR4A2CDK4CCND1CNR2 | |
| Indolylpropionic Acid SCHEMBL195405 | 0.82 | MAPT (0.68) | HPGDCYP2C19CDK4FAAHMPO | |
| Indolylpropionic Acid SCHEMBL29521227 | 0.82 | MAPT (0.68) | HPGDCYP2C19CDK4FAAHMPO | |
| Indolylpropionic Acid SCHEMBL29374161 | 0.82 | MAPT (0.68) | HPGDCYP2C19CDK4FAAHMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | POR, CYP4F3, CBR3 | HPGD 245/4885CYP2C19 239/4885ICMT 2908/4885 |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | POR, CYP4F3, CBR3 | HPGD 245/4885CYP2C19 239/4885ICMT 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.