SCHEMBL23701757

SCHEMBL23701757

O=C(O)Cc1c[nH]c2ccc(-c3ccccc3)cc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.66
ALDH1A1 P00352 2/20 0.66
HPGD P15428 2/20 0.66
LMNA P02545 1/20 0.66
GLA P06280 1/20 0.66
CYP2C9 P11712 1/20 0.66
NFKB1 P19838 1/20 0.66
PMP22 Q01453 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
ICMT O60725 8/20 0.64
CNR2 P34972 1/20 0.60
KDM4E B2RXH2 2/20 0.59
NR4A2 P43354 1/20 0.55
SCN9A Q15858 2/20 0.53
MEN1 O00255 1/20 0.51
MAPT P10636 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NR4A1 P22736 1/20 0.51
TRPV1 Q8NER1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30261856 1.00 TSHR (0.66) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL23701731 0.89 ALDH1A1 (0.59) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL6509009 0.88 TSHR (0.62) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL2008370 0.88 ICMT (0.81) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL24612560 0.88 TSHR (0.58) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL23701770 0.88 ICMT (0.79) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL29486513 0.88 TSHR (0.58) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL21392213 0.85 HPGD (0.66) HPGDICMTCNR2NR4A2SCN9A
SCHEMBL23718989 0.85 NR4A2 (0.62) TSHRALDH1A1HPGDLMNAGLA
SCHEMBL23701748 0.85 TSHR (0.58) TSHRALDH1A1HPGDLMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250290916-A1 Chemically Induced Proximity Systems ANTIBODY ANALYTICS LIMITED (GB) 2025-09-18 US disclosed
EP-4519415-A2 CHEMICALLY INDUCED PROXIMITY SYSTEMS Antibody Analytics Limited (GB) 2025-03-12 EP disclosed
WO-2024185847-A1 GENETICALLY MODIFIED MOUSE 国立研究開発法人理化学研究所 2024-09-12 WO disclosed
US-20240158735-A1 METHODS AND COMPOSITIONS USING AN ENGINEERED RELEASE FACTOR OXFORD FINANCE LLC, AS COLLATERAL AGENT 2024-05-16 US disclosed
WO-2023214183-A2 CHEMICALLY INDUCED PROXIMITY SYSTEMS ANTIBODY ANALYTICS LIMITED (GB) 2023-11-09 WO disclosed
EP-4001414-A1 NONHUMAN ANIMAL AND USE FOR SAME Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) 2022-05-25 EP disclosed
CN-114144400-A Kit of auxin degradation determining subsystem and application thereof 大学共同利用机关法人信息系统研究机构 2022-03-04 CN disclosed
CN-114127294-A Non-human animals and uses thereof 大学共同利用机关法人信息系统研究机构 2022-03-01 CN disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB TSHR 57/4885ALDH1A1 3460/4885HPGD 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.