SCHEMBL21392328

CCCC[C@H](NC(C)=O)C(=O)NC1CCC(=O)NCCC(C(=O)N[C@@H](Cc2cccc3ccccc23)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(Cc2ccccc2)NC(=O)CNC1=O

nearest known ligand 0.58

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	16/20	0.58

▸	MC1R	Q01726	10/20	0.58

▸	FURIN	P09958	1/20	0.53

▸	GNAI1	P63096	2/20	0.49

▸	MC3R	P41968	7/20	0.45

▸	MC5R	P33032	3/20	0.45

▸	BCL2L1	Q07817	1/20	0.43

▸	BAD	Q92934	1/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21392362	0.93	MC4R (0.68)	MC4RMC1RMC3RMC5R
SCHEMBL21392327	0.91	MC4R (0.60)	MC4RMC1RFURINMC3RMC5R
SCHEMBL12657701	0.91	MC4R (0.60)	MC4RMC1RFURINMC3RMC5R
SCHEMBL12657866	0.91	MC4R (0.60)	MC4RMC1RFURINMC3RMC5R
SCHEMBL22606203	0.91	MC4R (0.60)	MC4RMC1RFURINMC3RMC5R
SCHEMBL21392454	0.90	MC4R (0.52)	MC4RMC1RFURINMC3RMC5R
SCHEMBL12657870	0.89	MC4R (0.73)	MC4RMC1RMC3RMC5R
SCHEMBL22606146	0.89	MC4R (0.73)	MC4RMC1RMC3RMC5R
SCHEMBL22606182	0.89	MC4R (0.73)	MC4RMC1RMC3RMC5R
SCHEMBL20206289	0.88	MC4R (0.57)	MC4RMC1RFURINGNAI1MC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019183472-A1	MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY	PALATIN TECHNOLOGIES, INC. (US)	2019-09-26	—	—	WO	disclosed