SCHEMBL22606182

SCHEMBL22606182

CCCC[C@H](NC(C)=O)C(=O)N[C@H]1CCC(=O)NCC[C@@H](C(=O)NC(Cc2c[nH]c3ccccc23)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(=N)N)NC1=O

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 13/20 0.73
▸ MC1R Q01726 8/20 0.73
▸ MC5R P33032 3/20 0.54
▸ MC3R P41968 3/20 0.54
▸ F12 P00748 4/20 0.53
▸ IL23R Q5VWK5 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12657870 1.00 MC4R (0.73) MC4RMC1RMC5RMC3RF12
SCHEMBL22606146 1.00 MC4R (0.73) MC4RMC1RMC5RMC3RF12
SCHEMBL15127364 0.99 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL15127367 0.99 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL22605979 0.98 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL21392385 0.98 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL20362980 0.98 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL12657710 0.98 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL22606179 0.98 MC4R (0.71) MC4RMC1RMC5RMC3RF12
SCHEMBL15127368 0.98 MC4R (0.71) MC4RMC1RMC5RMC3RF12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy PALATIN TECHNOLOGIES, INC. (US) 2022-03-29 — — US disclosed
US-20200339631-A1 Melanocortin-1 Receptor-Specific Peptides for Cytokine Storm and Inflammation Therapy PALATIN TECHNOLOGIES INC (US) 2020-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy MC3R, MC1R, MC2R MC4R 6/4885MC1R 2/4885MC5R 7/4885
US-20200339631-A1 Melanocortin-1 Receptor-Specific Peptides for Cytokine Storm and Inflammation Therapy MC3R, MC1R, MC2R MC4R 6/4885MC1R 2/4885MC5R 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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