Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 7/20 | 0.45 |
| ▸ | CDK2 | P24941 | 7/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 8/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 8/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 8/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 8/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 8/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 8/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17998701 | 0.84 | CDK2 (0.61) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL5025187 | 0.81 | CDK2 (0.51) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL2878400 | 0.80 | CCNE1 (0.44) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL31242783 | 0.78 | CCNE1 (0.43) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL1903375 | 0.77 | CCNE1 (0.44) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL28847719 | 0.76 | CCNE1 (0.44) | CCNE1CDK2CDK5CDK1CDK4 | |
| SCHEMBL8834765 | 0.76 | CCNE1 (0.52) | CCNE1CDK2CDK5CDK1CDK4 | |
| SCHEMBL29148603 | 0.76 | CCNE1 (0.41) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL15839429 | 0.75 | SMN1; SMN2 (0.46) | CCNE1CDK2CDK5CDK1CDK4 | |
| SCHEMBL5029576 | 0.75 | CDK2 (0.46) | CCNE1CDK2CDK5PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800771-B2 | Process for the preparation of dasatinib polymorph | NATCO PHARMA LIMITED (IN) | 2020-10-13 | — | — | US | disclosed |
| US-20190292177-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF DASATINIB POLYMORPH | NATCO PHARMA LIMITED (IN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800771-B2 | Process for the preparation of dasatinib polymorph | ABL1, NOP56, SRSF6 | CCNE1 1871/4885CDK2 1074/4885CDK5 467/4885 |
| US-20190292177-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF DASATINIB POLYMORPH | NOP56, ABL1, SRSF6 | CCNE1 2012/4885CDK2 1283/4885CDK5 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.