NOP56 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL4699731	1.00	2/20
SCHEMBL16111548	1.00	2/20
SCHEMBL29358745	1.00	2/20
SCHEMBL29380618	1.00	2/20
SCHEMBL29931136	1.00	2/20
SCHEMBL4697866	0.89	2/20
SCHEMBL24532075	0.89	2/20
SCHEMBL4697696	0.86	2/20
SCHEMBL23092285	0.86	2/20
SCHEMBL29688472	0.86	2/20
SCHEMBL22024695	0.86	2/20
SCHEMBL16136600	0.84	2/20
SCHEMBL24532058	0.83	2/20
SCHEMBL4699947	0.83	2/20
SCHEMBL22025026	0.82	2/20
SCHEMBL22119546	0.82	2/20
SCHEMBL24532062	0.82	2/20
SCHEMBL18804561	0.81	2/20
SCHEMBL22024561	0.81	2/20
SCHEMBL22025030	0.81	2/20

Clinical trials — most relevant to NOP56 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Fludarabine, Mitoxantrone, and Dexamethasone (FND) Plus Rituximab for Lymphoma Patients	PHASE3	COMPLETED
Safety and Efficacy of Pentostatin and Low Dose TBI With Allogenic Peripheral Blood Stem Cell Transplant	PHASE2	COMPLETED
A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL	PHASE1/PHASE2	RECRUITING
SGI-110 and Donor Lymphocyte Infusions (DLI) After Allogeneic Stem Cell Transplantation	PHASE2	UNKNOWN
Genetic Changes in Patients With Non-Small Cell Lung Cancer Who Are Receiving Vinorelbine and Gemcitabine Before Surgery	PHASE2	COMPLETED
Biologic Correlative Taxotere/AC	PHASE2	COMPLETED
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma	PHASE2	COMPLETED
Nucleoside Therapy in Patients With Telomere Biology Disorders	PHASE1	RECRUITING
A Phase I Study to Evaluate the Safety and Immunogenicity of PnuBioVax	PHASE1	COMPLETED
Molecular Genetics Study of Nasopharyngeal Carcinoma: Characterization of NCP Susceptibility Gene(s)	nan	COMPLETED
iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy	nan	COMPLETED
Impact of Bariatric and Metabolic Surgery on the Reduction of Premature Aging.	nan	COMPLETED
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients	nan	RECRUITING
The Efficiency of Postoperative Interferon-alpha Treatment in p48 Positive Patients With Hepatocellular Carcinoma	nan	WITHDRAWN
Neuroblastoma Precision Trial	nan	ACTIVE_NOT_RECRUITING
Amplification of Zinc Finger Protein 217 Gene in Multiple Myeloma	nan	UNKNOWN
Emerging Role of NOTCH-related Long Non-coding RNA(s) as Biomarkers in Liquid Biopsy From Colorectal Cancer Patients	nan	COMPLETED
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia	nan	NOT_YET_RECRUITING
Study of Specimens From Young Patients With Neuroblastoma	nan	COMPLETED
Role of the Nuclear Pore Component RANBP2 in Inflammatory Responses to Viral Infections	nan	COMPLETED
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma	nan	COMPLETED
Telomeres Length in Israeli Fibrotic ILD Patients	nan	ENROLLING_BY_INVITATION
S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma	nan	COMPLETED
Selinexor (Nexpovio®) (SVd) in Patients With Relapsed or Refractory Multiple Myeloma	nan	ACTIVE_NOT_RECRUITING
Quantitative Assessment of the Etiologies of Megalencephaly Associated With a Detectable Tumor Risk	nan	NOT_YET_RECRUITING
Micro Ribosomal Nucleic Acid 155 in Non Hodgkin Lymphoma	nan	COMPLETED
Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs	nan	UNKNOWN
Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas	nan	ACTIVE_NOT_RECRUITING
Molecular Mechanism of Nasopharyngeal Carcinoma	nan	UNKNOWN
Whole Genome Scan of Extended Families With Familial Vocal Cord Paralysis	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a NOP56 binder may also engage these)

Protein	Name	Similarity
Q95K50	—	1.000	Q95K50 →
Q5RA29	—	1.000	Q5RA29 →
Q3SZ63	—	1.000	Q3SZ63 →
Q9D6Z1	—	1.000	Q9D6Z1 →
Q9MAB3	—	1.000	Q9MAB3 →
Q12460	—	0.998	Q12460 →
Q9P7S7	—	0.997	Q9P7S7 →
Q5B8G3	—	0.995	Q5B8G3 →
Q8X066	—	0.995	Q8X066 →
Q4R779	—	0.994	Q4R779 →
Q54MT2	—	0.994	Q54MT2 →
A3LUT0	—	0.994	A3LUT0 →
A2QE38	—	0.994	A2QE38 →
A6ZPE5	—	0.994	A6ZPE5 →
A5E4V9	—	0.994	A5E4V9 →
A6RMY5	—	0.993	A6RMY5 →
NOP58	Nucleolar protein 58	0.993	landscape →
Q12499	—	0.993	Q12499 →
Q59S06	—	0.993	Q59S06 →
Q21276	—	0.993	Q21276 →
P0CP26	—	0.993	P0CP26 →
Q4WYK9	—	0.993	Q4WYK9 →
Q6CKR8	—	0.993	Q6CKR8 →
A7F2R6	—	0.992	A7F2R6 →
A1D688	—	0.992	A1D688 →
Q753I4	—	0.992	Q753I4 →
Q6CG46	—	0.992	Q6CG46 →
Q4PBF2	—	0.992	Q4PBF2 →
Q6FQ21	—	0.992	Q6FQ21 →
A6QYH8	—	0.991	A6QYH8 →