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SCHEMBL21392400

SCHEMBL21392400

CCCC[C@H](NC(C)=O)C(=O)NC1CCC(=O)NCCC(C(=O)N[C@@H](CCCCN)C(N)=O)NC(=O)CNC(=O)C(Cc2ccccc2)NC(=O)CNC1=O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 6/20 0.53
▸ MC1R Q01726 4/20 0.53
▸ TNKS2 Q9H2K2 3/20 0.47
▸ OPRM1 P35372 1/20 0.44
▸ OPRD1 P41143 1/20 0.44
▸ OPRK1 P41145 1/20 0.44
▸ APLNR P35414 1/20 0.44
▸ FURIN P09958 1/20 0.43
▸ SIRT2 Q8IXJ6 1/20 0.42
▸ SIRT1 Q96EB6 1/20 0.42
▸ SIRT3 Q9NTG7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392282 0.91 MC4R (0.54) MC4RMC1RTNKS2APLNR
SCHEMBL21392357 0.88 MC4R (0.68) MC4RMC1R
SCHEMBL21392389 0.84 MC4R (0.45) MC4RMC1ROPRM1OPRD1OPRK1
SCHEMBL21392372 0.84 MC4R (0.49) MC4RMC1R
SCHEMBL20206283 0.84 MC4R (0.55) MC4RMC1R
SCHEMBL21392336 0.83 MC4R (0.61) MC4RMC1R
SCHEMBL21392447 0.82 MC4R (0.54) MC4RMC1R
SCHEMBL21392453 0.81 MC4R (0.47) MC4RMC1R
SCHEMBL21392328 0.81 MC4R (0.58) MC4RMC1RFURIN
SCHEMBL21392471 0.81 MC4R (0.50) MC4RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183472-A1 MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY PALATIN TECHNOLOGIES, INC. (US) 2019-09-26 — — WO disclosed
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