Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.47 |
| ▸ | MC1R | Q01726 | 5/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.45 |
| ▸ | FURIN | P09958 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.43 |
| ▸ | MC5R | P33032 | 3/20 | 0.43 |
| ▸ | MC3R | P41968 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | NPY4R | P50391 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12092579 | 1.00 | MC4R (0.47) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL20362997 | 1.00 | MC4R (0.47) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL12092650 | 0.95 | MC4R (0.47) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL21392265 | 0.94 | MC4R (0.48) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL20206212 | 0.94 | MC4R (0.48) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL12092580 | 0.94 | MC4R (0.48) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL12092735 | 0.94 | MC4R (0.47) | MC4RMC1RSIRT2SIRT1SIRT3 | |
| SCHEMBL12092629 | 0.94 | MC4R (0.52) | MC4RMC1RFURINMC5RMC3R | |
| SCHEMBL20206361 | 0.94 | MC4R (0.52) | MC4RMC1RFURINMC5RMC3R | |
| SCHEMBL21392480 | 0.94 | MC4R (0.43) | MC4RMC1RSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183472-A1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY | PALATIN TECHNOLOGIES, INC. (US) | 2019-09-26 | — | — | WO | disclosed |