Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | STS | P08842 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392497 | 0.92 | PTPN2 (0.56) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL29848355 | 0.86 | ALDH1A1 (0.55) | PTPN2PTPN1PTPN6KDM4EALDH1A1 | |
| SCHEMBL18547071 | 0.86 | ALDH1A1 (0.55) | PTPN2PTPN1PTPN6KDM4EALDH1A1 | |
| SCHEMBL18547146 | 0.83 | ALDH1A1 (0.54) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL13125050 | 0.82 | NPSR1 (0.61) | KDM4EALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL14447535 | 0.82 | PTPN2 (0.55) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL29847387 | 0.82 | HDAC1 (0.48) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL29847380 | 0.82 | HDAC1 (0.48) | KDM4EALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL14447471 | 0.82 | PTPN2 (0.62) | PTPN2PTPN1PTPN6ABL1RIN1 | |
| SCHEMBL18554650 | 0.81 | ALDH1A1 (0.54) | PTPN2PTPN1PTPN6ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292189-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292189-A1 | LIM KINASE INHIBITORS | LIMK1, LIMK2, LIMA1 | PTPN2 3645/4885PTPN1 3611/4885PTPN6 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.