⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690033 | 0.61 | — | — | |
| SCHEMBL4788913 | 0.57 | — | — | |
| SCHEMBL17734083 | 0.57 | — | — | |
| SCHEMBL4475264 | 0.57 | — | — | |
| SCHEMBL12370560 | 0.57 | — | — | |
| SCHEMBL14781231 | 0.54 | — | — | |
| SCHEMBL16485585 | 0.52 | — | — | |
| SCHEMBL19675434 | 0.52 | — | — | |
| SCHEMBL17125674 | 0.49 | — | — | |
| SCHEMBL17191104 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180631-A1 | SUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES AS PRMT5 INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2019-09-26 | — | — | WO | disclosed |