Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724677 | 0.83 | ASAH1 (0.54) | L3MBTL1TSHRALDH1A1GAAPSMD14 | |
| SCHEMBL18746208 | 0.80 | SMN1; SMN2 (0.45) | L3MBTL1TSHRALDH1A1MAPK1GAA | |
| SCHEMBL16341726 | 0.80 | MEN1 (0.45) | L3MBTL1TSHRALDH1A1MAPTPKM | |
| SCHEMBL21778282 | 0.80 | CNR2 (0.54) | L3MBTL1TSHRALDH1A1MAPTPKM | |
| SCHEMBL26300800 | 0.80 | CNR2 (0.54) | L3MBTL1TSHRALDH1A1GAAPSMD14 | |
| SCHEMBL723691 | 0.79 | PARP1 (0.54) | L3MBTL1TSHRALDH1A1MAPTGAA | |
| SCHEMBL10333054 | 0.76 | GAA (0.43) | L3MBTL1TSHRALDH1A1MAPTPKM | |
| SCHEMBL15294671 | 0.75 | NPSR1 (0.54) | L3MBTL1TSHRMAPTMAPK1GAA | |
| SCHEMBL26376969 | 0.75 | KDM4E (0.42) | L3MBTL1TSHRALDH1A1MAPTPKM | |
| SCHEMBL8362182 | 0.75 | L3MBTL1 (0.68) | L3MBTL1TSHRALDH1A1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11065608-B2 | Multidentate ligands and use thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2021-07-20 | — | — | US | disclosed |
| US-20190291088-A1 | MULTIDENTATE LIGANDS AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2019-09-26 | — | — | US | disclosed |