Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.38 |
| ▸ | ATG7 | O95352 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 2/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26212473 | 0.89 | DNMT3B (0.37) | DNMT3BBCHENT5ESLC29A1FDPS | |
| SCHEMBL7983071 | 0.84 | DNMT3B (0.41) | DNMT3BBCHENT5ESLC29A1FDPS | |
| SCHEMBL7983075 | 0.84 | DNMT3B (0.41) | DNMT3BBCHENT5ESLC29A1FDPS | |
| SCHEMBL8510067 | 0.84 | DNMT3B (0.41) | DNMT3BBCHENT5ESLC29A1FDPS | |
| SCHEMBL21393003 | 0.81 | BCHE (0.49) | BCHESLC29A1 | |
| SCHEMBL21393030 | 0.80 | ALDH1A1 (0.40) | DNMT3BATG7FDPSHDAC1HDAC6 | |
| SCHEMBL21393157 | 0.76 | ALDH1A1 (0.48) | — | |
| SCHEMBL21636995 | 0.74 | STING1 (0.47) | NT5E | |
| SCHEMBL12174029 | 0.73 | SLC29A1 (0.47) | DNMT3BSLC29A1 | |
| SCHEMBL2578051 | 0.73 | SLC29A1 (0.47) | DNMT3BSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242212-A2 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | Takeda Pharmaceutical Company Limited (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |