Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 12/20 | 0.50 |
| ▸ | RAB9A | P51151 | 10/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27836536 | 0.98 | NCF1 (0.57) | NCF1NPC1RAB9AKMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL27836524 | 0.98 | NCF1 (0.57) | NCF1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL14536426 | 0.80 | NCF1 (0.59) | NCF1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL22926862 | 0.78 | BACE1 (0.53) | NCF1NPC1RAB9A | |
| SCHEMBL4937771 | 0.77 | NCF1 (0.65) | NCF1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL4937770 | 0.77 | NCF1 (0.65) | NCF1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL30760998 | 0.76 | NCF1 (0.71) | NCF1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL10458402 | 0.76 | NCF1 (0.71) | NCF1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL1998487 | 0.76 | PDGFRB (0.56) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL22545240 | 0.76 | NCF1 (0.53) | NCF1NPC1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458985-B | 6-heteroaryloxy-and 6-aryloxy-quinoline-2-carboxamides and their use | 艾伯维公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109641886-A | bicyclic BET bromodomain inhibitors and uses thereof | 康威基内有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-106467541-B | Substituted quinolone analog derivative or its pharmaceutically acceptable salt or stereoisomer and its Pharmaceutical composition and application | 暨南大学 | 2019-04-05 | — | — | CN | claimed |
| CN-109232396-A | Amide pyridine derivatives and application thereof | 聊城大学 | 2019-01-18 | — | — | CN | claimed |
| CN-108727416-A | The miscellaneous aroma system amide derivatives of tricyclic and its preparation and use | 北京大学 | 2018-11-02 | — | — | CN | claimed |
| CN-108697709-A | Methods for treating huntington's disease | PTC医疗公司 | 2018-10-23 | — | — | CN | claimed |
| CN-104755083-B | Urea and amide derivatives of aminoalkyl piperazine and application thereof | 南方研究所 | 2018-04-10 | — | — | CN | claimed |
| CN-105636953-B | 1,4 dibasic pyridyl derivatives and its purposes for treating the illness related to SMN shortages | 诺华股份有限公司 | 2018-01-02 | — | — | CN | claimed |
| CN-107428729-A | COMPOUNDS FOR THE TREATMENT OF CANCER | 豪夫迈·罗氏有限公司 | 2017-12-01 | — | — | CN | claimed |
| CN-107001345-A | Hete rocyclic derivatives and application thereof | 株式会社C&C新药研究所 | 2017-08-01 | — | — | CN | claimed |
| CN-102917590-A | Trycyclic compounds and pbk inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2013-02-06 | — | — | CN | claimed |
| CN-102388053-A | Hydroxythienoquinolones and related compounds as anti-infective agents | ACHILLION PHARMACEUTICALS INC | 2012-03-21 | — | — | CN | claimed |
| CN-102105437-A | Adamantyl diamide derivatives and uses of same | LUNDBECK & CO AS H | 2011-06-22 | — | — | CN | claimed |
| CN-101990433-A | Compounds that enhance atoh-1 expression | BRIGHAM & WOMENS HOSPITAL | 2011-03-23 | — | — | CN | claimed |
| CN-100475207-C | 1H-imidazo[4,5-c]quinoline derivatives in the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2009-04-08 | — | — | CN | claimed |
| CN-1867572-A | proteasome inhibitors and methods of use thereof | CEPHALON INC (US) | 2006-11-22 | — | — | CN | claimed |
| CN-1655788-A | 1H-imidazo[4,5-c]quinoline derivatives in the treatment of protein kinase dependent diseases | NOVARTIS AG (CH) | 2005-08-17 | — | — | CN | claimed |
| US-5919928-A | Phenanthridine derivatives and metal complexes thereof used for transparent recording medium or optical recording medium | NIPPON PAPER INDUSTRIES, CO., LTD. (JP) | 1999-07-06 | — | — | US | claimed |
| US-5892042-A | OPTICAL RECORDING MEDIA WITH ACRIDINE DYES ON TRANSPARENT SUBSTRATE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1999-04-06 | — | — | US | claimed |
| US-5792863-A | HAVING LARGE ABSORPTION IN NEAR INFRARED, REDUCED ABSORPTION IN VISIBLE RANGE | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-08-11 | — | — | US | claimed |