Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17946216 | 0.88 | CHRM2 (0.38) | P2RX7PTGER4CHRM2CHRM4CHRM5 | |
| SCHEMBL11929362 | 0.88 | CHRM2 (0.38) | P2RX7PTGER4CHRM2CHRM4CHRM5 | |
| SCHEMBL12301043 | 0.88 | CHRM2 (0.38) | P2RX7PTGER4CHRM2CHRM4CHRM5 | |
| SCHEMBL21393382 | 0.79 | — | — | |
| SCHEMBL10587336 | 0.76 | CHRM2 (0.45) | P2RX7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL10491078 | 0.74 | P2RX7 (0.37) | P2RX7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9066543 | 0.73 | CHRM2 (0.36) | P2RX7PTGER4CHRM2CHRM4CHRM5 | |
| SCHEMBL17946153 | 0.73 | CHRM2 (0.36) | P2RX7PTGER4CHRM2CHRM4CHRM5 | |
| SCHEMBL12324926 | 0.73 | PTGER4 (0.38) | PTGER4 | |
| SCHEMBL22114509 | 0.72 | PIK3CD (0.39) | P2RX7CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |