Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18758928 | 0.83 | MEN1 (0.53) | MEN1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL8668367 | 0.80 | MEN1 (0.53) | MEN1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL8668035 | 0.79 | PNP (0.53) | MEN1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL8667603 | 0.77 | PNP (0.60) | MEN1KMT2AALDH1A1LMNAPNP | |
| SCHEMBL8668254 | 0.76 | PNP (0.59) | MEN1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL3503364 | 0.74 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAPKM | |
| SCHEMBL22356561 | 0.73 | MEN1 (0.76) | MEN1KMT2AALDH1A1TLR7PNP | |
| SCHEMBL8673354 | 0.73 | MEN1 (0.62) | MEN1KMT2AALDH1A1TLR7PNP | |
| SCHEMBL8673356 | 0.73 | MEN1 (0.62) | MEN1KMT2AALDH1A1TLR7PNP | |
| Loxoribine SCHEMBL24635226 | 0.72 | MEN1 (1.00) | MEN1KMT2ALMNATLR7PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183216-A1 | COMPOSITIONS AND METHODS FOR CANCER TREATMENT | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-09-26 | — | — | WO | disclosed |