Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8667603 | 0.95 | PNP (0.60) | PNPMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL8668367 | 0.86 | MEN1 (0.53) | PNPMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL18758928 | 0.84 | MEN1 (0.53) | MEN1KMT2AHSD17B10HTTL3MBTL1 | |
| SCHEMBL23449156 | 0.81 | PNP (0.58) | PNPMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL21393356 | 0.79 | MEN1 (0.56) | PNPMEN1KMT2AMAPK1ADORA2A | |
| SCHEMBL835360 | 0.79 | TSHR (0.52) | MEN1KMT2AMAPK1HSD17B10HTT | |
| SCHEMBL23255226 | 0.78 | TSHR (0.56) | MEN1KMT2AMAPK1HSD17B10HTT | |
| SCHEMBL8668254 | 0.77 | PNP (0.59) | PNPMEN1KMT2AHTTPDE4A | |
| SCHEMBL837428 | 0.75 | MEN1 (0.55) | MEN1KMT2AMAPK1HSD17B10HTT | |
| SCHEMBL25572309 | 0.74 | CYP3A4 (0.50) | MEN1KMT2AHTTPDE4AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786359-A | IMMUNOSTIMULANTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-28 | — | — | US | claimed |
| US-5786359-A | IMMUNOSTIMULANTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-07-28 | — | — | US | disclosed |