SCHEMBL21393914

SCHEMBL21393914

CCCCC(C)N(/N=C/c1ccccc1C(=O)O)c1nc(-c2ccccc2Cl)cs1

nearest known ligand 0.90

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859822 0.95 DHODH (1.00) DHODH
SCHEMBL19631465 0.95 DHODH (1.00) DHODH
SCHEMBL19631460 0.91 DHODH (1.00) DHODH
SCHEMBL29859373 0.91 DHODH (1.00) DHODH
SCHEMBL29859351 0.88 DHODH (1.00) DHODH
SCHEMBL20836148 0.88 DHODH (1.00) DHODH
SCHEMBL19631440 0.88 DHODH (1.00) DHODH
SCHEMBL20836118 0.87 DHODH (0.87) DHODH
SCHEMBL29859499 0.87 DHODH (0.87) DHODH
SCHEMBL20836117 0.87 DHODH (0.87) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190292162-A1 THIAZOLE DERIVATIVE AND APPLICATIONS EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2019-09-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292162-A1 THIAZOLE DERIVATIVE AND APPLICATIONS DHODH, DLD, THOC2 DHODH 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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