Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 17/20 | 0.75 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.51 |
| ▸ | RICTOR | Q6R327 | 2/20 | 0.51 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.51 |
| ▸ | MAPKAP1 | Q9BPZ7 | 2/20 | 0.51 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748722 | 0.87 | MTOR (1.00) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21393941 | 0.78 | MTOR (0.81) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL17748629 | 0.78 | MTOR (1.00) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21354081 | 0.77 | MTOR (0.75) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL24055114 | 0.75 | MTOR (0.84) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL21375688 | 0.75 | MTOR (0.74) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL29564081 | 0.74 | MTOR (0.85) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL23505793 | 0.74 | MTOR (0.85) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL17748729 | 0.74 | MTOR (0.85) | MTORPIK3CAPIK3R1RICTORRPTOR | |
| SCHEMBL24398831 | 0.74 | MTOR (0.70) | MTORPIK3CAPIK3R1RICTORRPTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186591-B2 | Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines | UNIVERSITÄT BASEL (CH) | 2021-11-30 | — | — | US | disclosed |
| US-10993947-B2 | Treatment of skin lesions | TORQUR (CH) | 2021-05-04 | — | — | US | disclosed |
| US-20200277304-A1 | DIFLUOROMETHYL-AMINOPYRIDINES AND DIFLUOROMETHYL-AMINOPYRIMIDINES | TORQUR AG (CH) | 2020-09-03 | — | — | US | disclosed |
| US-20190290653-A1 | TREATMENT OF SKIN LESIONS | TORQUR AG (CH) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10993947-B2 | Treatment of skin lesions | CXCR3, CCR3, C3AR1 | MTOR 4107/4885PIK3CA 3971/4885PIK3R1 3358/4885 |
| US-20200277304-A1 | DIFLUOROMETHYL-AMINOPYRIDINES AND DIFLUOROMETHYL-AMINOPYRIMIDINES | PIK3CA, MTOR, PIKFYVE | MTOR 2/4885PIK3CA 1/4885PIK3R1 30/4885 |
| US-20190290653-A1 | TREATMENT OF SKIN LESIONS | CXCR3, CCR3, C3AR1 | MTOR 4107/4885PIK3CA 3971/4885PIK3R1 3358/4885 |
| US-11186591-B2 | Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines | PIK3CA, MTOR, PIKFYVE | MTOR 2/4885PIK3CA 1/4885PIK3R1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.