SCHEMBL21394130

SCHEMBL21394130

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)C4(c6ccccc6-c6ccccc64)c4ccccc4N5c4ccccc4)n3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
LMNA P02545 2/20 0.36
PDE6D O43924 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 2/20 0.35
PDK2 Q15119 3/20 0.35
ADAMTS5 Q9UNA0 1/20 0.34
NTSR1 P30989 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GLA P06280 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21394134 1.00 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394129 1.00 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394133 0.99 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394076 0.97 PDK2 (0.37) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394078 0.97 PDK2 (0.37) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394052 0.97 PDK2 (0.37) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394079 0.97 PDK2 (0.37) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394077 0.96 PDE6D (0.36) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394054 0.96 PDE6D (0.36) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL21394135 0.96 PDE6D (0.36) ALDH1A1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-20220123218-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG CHEM, LTD. (KR) 2022-04-21 US disclosed
US-11239425-B2 Organic light emitting device LG CHEM, LTD. (KR) 2022-02-01 US disclosed
US-20190296243-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-09-26 US disclosed