Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355353 | 1.00 | RAB9A (0.42) | RAB9AFSCN1GPR52CACNA1HGPR6 | |
| SCHEMBL21394800 | 0.93 | EP300 (0.42) | RAB9AGPR52CACNA1HEP300 | |
| SCHEMBL21394588 | 0.88 | RAB9A (0.42) | RAB9APARP1 | |
| SCHEMBL29357018 | 0.88 | RAB9A (0.42) | RAB9APARP1 | |
| SCHEMBL22479674 | 0.86 | RAB9A (0.44) | RAB9AFSCN1GPR52 | |
| SCHEMBL29354561 | 0.85 | RAB9A (0.44) | RAB9AGPR52PARP1 | |
| SCHEMBL21394549 | 0.85 | RAB9A (0.44) | RAB9AGPR52PARP1 | |
| SCHEMBL29356974 | 0.85 | RAB9A (0.46) | RAB9AGPR52PARP1 | |
| SCHEMBL21384478 | 0.85 | RAB9A (0.46) | RAB9AGPR52PARP1 | |
| SCHEMBL21394752 | 0.85 | RAB9A (0.41) | RAB9AGPR52EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |