Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21383987 | 0.69 | BRD4 (0.33) | KDM4EALDH1A1GAA | |
| SCHEMBL11249244 | 0.67 | KDM4E (0.48) | PDE4DKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20138860 | 0.66 | SMN1; SMN2 (0.50) | PDE4DKDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL20139038 | 0.66 | KDM4E (0.50) | PDE4DKDM4EALDH1A1SMN1; SMN2PDE4A | |
| SCHEMBL21395225 | 0.66 | TP53 (0.37) | GAA | |
| SCHEMBL8930592 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL30231063 | 0.64 | LOX (0.46) | PDE4DALDH1A1SMN1; SMN2GAA | |
| SCHEMBL2021592 | 0.62 | — | — | |
| SCHEMBL10182573 | 0.62 | — | — | |
| SCHEMBL4181392 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |